Starting with F_0 and working one's way up step by step, one finds
F_1(x)=x, F_2(x)=x(x+2), F_3(x)=x(x+3)^2. So one conjectures that
F_n(x)=x(x+n)^(n-1), and this is readily seen to satsify the given
differential-difference equations.
Hence F_300(7)=7*(307)^299 and this is already the prime factorization since 307 is a prime.